Health & Safety - Vaccinations:
There's nothing like updating vaccinations to make you feel like a human pin cushion. I remember one such visit several years ago when, after several shots, the nurse turned to me and said "Well, I think we've more or less filled this arm up. Perhaps it's better we continue on the other arm.' Fortunately, our visit to the George Washington University Travel Clinic was a fairly painless affair as most of our vaccinations are still up-to-date from previous travels. Even still, we didn't leave totally unscathed. Here’s a brief summary of the immunizations and medications we have for the expedition. All descriptions are provided by
masta.org.

Hepatitis A: This is a viral disease which affects the liver. Symptoms include fever, chills, weakness, loss of appetite, nausea and abdominal discomfort, followed within a few days by jaundice (yellowing of the skin and the whites of the eyes). The urine may become dark and the stools pale. Many infections, particularly in children, are mild. Occasionally, jaundice may be severe and liver failure may occur. In adults, up to 2% of cases are fatal. In general, severity of the disease increases with age. Past infection with hepatitis A gives life-long immunity. The disease is commonly associated with eating and drinking contaminated food and water. Outbreaks are often linked to raw or undercooked shellfish and raw vegetables. The disease occurs worldwide, but is more common in developing countries with poor sanitation and overcrowding.

Hepatitis B: This is a viral infection affecting the liver. Symptoms include loss of appetite, nausea,
abdominal pain and sometimes a rash, joint pain and jaundice. The urine may become dark and the stools pale. Children under 1 year of age usually have no symptoms but virtually all such children become carriers of the disease for life. About 5% of adult sufferers will go on to become carriers. Hepatitis B carriers can infect other people and are at risk of death from liver disease/cancers years after the initial infection. Hepatitis B is transmitted through exposure to infected blood and body fluids. It may be acquired from infected blood transfusions, contact with unsterilized medical equipment and by unprotected sexual intercourse.

Meningitis (Meningococcal Serogroups A, C, Y, W-135): This is a bacterial infection affecting the tissues lining the brain and spinal cord. Symptoms include fever, intense headache, nausea, stiff neck, inability to tolerate bright light and fine blotchy rash. If not treated early, the disease may be fatal within hours. Cases occur worldwide. An area of particularly high incidence, especially during the dry season, exists in the sub-Saharan region of Africa known as the “meningitis belt”. Meningococcal meningitis can occur in epidemics, especially where large crowds gather. The bacteria are transmitted by droplets or direct contact with carriers or infected persons. Carriers are those who have the bacteria present in their nose and throat but do not become infected with the disease themselves.

Polio (Oral): Polio is a viral infection. The World Health Organization has initiated a global polio eradication program but some countries are still reporting new cases (e.g. India, Nigeria, Pakistan and Afghanistan). The initial symptoms are fever, headache and vomiting as the virus multiplies in the gut. The virus then invades the blood and nervous system. Paralysis occurs in less than 1 in 100 cases of infection, this risk increases with age. The virus is spread from person to person through either mucous from the nose and throat or by contamination of food/drink with infected feces.

Rabies: Rabies is a viral disease primarily affecting animals but humans can also be infected. The virus travels from the site of entry (the bite or scratch) via the nerves to the brain and spinal cord and eventually spreads to the salivary glands. Symptoms start with itching and tingling at the site of the healed bite and then rapidly progresses to include headache, fever, spreading paralysis, confusion and aggression and hydrophobia (fear of water). It may take many weeks or months for symptoms to develop although it is usually 2-8 weeks (but can in rare circumstances be a short as 4 days). Unfortunately, once symptoms have developed, rabies is fatal.

Rabies can be transmitted in a number of ways to humans. Dog bites are by far the most common source of infection. A scratch to the skin, a lick on a fresh skin break or contact of the infected saliva with intact mucous membranes may also transmit rabies. Cats, bats, foxes, skunks, raccoons, monkeys and many other animals can also be infected with this virus. Animals may be infectious for five days before they develop symptoms.

Tetanus: Tetanus is caused by a bacteria which releases a powerful toxin into the body. Symptoms include jaw stiffness (lock-jaw), and difficulty swallowing. The toxin also causes severe and very painful muscle spasms. These spasms may interfere with breathing and lead to death. Tetanus spores are present worldwide in soil and may be introduced into the body during injury through a puncture wound, burn or trivial, unnoticed wounds. Travelers are often more vulnerable to injury and may find local medical facilities inadequate.

Typhoid Fever (Oral): Typhoid is caused by a bacterium (Salmonella typhi). The Illness is usually characterized by fever, loss of appetite, lethargy and a change in bowel habits. Constipation is common but diarrhea can also occur. Without treatment, typhoid can be fatal, with perforation of the gut producing peritonitis or severe bleeding. Paratyphoid fever is similar but tends to be less severe. Transmission is by ingesting food and water contaminated by the typhoid bacterium. Outbreaks have occurred when water supplies have been contaminated by raw sewage. Raw or undercooked shellfish pose a particular risk.

Yellow Fever: Yellow fever is a viral infection, transmitted by the bite of an infected mosquito,
that may cause a flu-like illness with symptoms including fever, chills, headaches and muscular pain. In the more severe form of the disease, the virus can affect the liver causing jaundice and bleeding. The death rate can be over 50% in Western travelers. Yellow fever is principally a disease of jungle areas but there are occasional outbreaks in towns and cities. It occurs in Africa, the Americas and some Caribbean Islands.
   
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